Acetyl-L-carnitine facilitates the movement of fatty acids into mitochondria, where they can be burned as fuel to produce energy. Thus, acetyl-L-carnitine helps to support whole-body energy production. Acetyl-L-carnitine supplementation has been shown to benefit energy-intensive body systems such as the nervous system and the cardiovascular system, and to help counteract the age-related increase in oxidative stress and the decrease in mitochondrial efficiency that occurs with advancing years. Acetyl-l-carnitine has wide-ranging benefits for nervous system wellness, including the central and peripheral nervous systems, and cognitive health, as well as positive mood. It has been shown to promote peripheral nervous system comfort, support healthy mood, energy and overall well-being.