Curcumin+ features BCM-95®—a 100% pure turmeric extract standardized to curcumin, demethoxycurcumin, bisdemethoxycurcumin, and essential oils of turmeric rhizome. With optimal composition and bioavailability, BCM-95 brings top-of-the-line clinical impact in a rare to the marketplace, additive-free delivery.
- SUPPLEMENT FACTS
Serving size: 1 Capsule Amount % Daily
Servings per container: 120 Per Serving Value
BCM-95® Turmeric Extract (Curcuma longa)(rhizome) (95% total 500 mg **
curcuminoids complex, including curcumin, curcuminoids, and
volatile oils) (86% curcuminoids)(65% curcumin)
** Daily Value Not Established
Other Ingredients: HPMC (capsule), dicalcium phosphate, ascorbyl palmitate, silica, and
carboxymethyl cellulose.
Does Not Contain: Wheat, gluten, corn, yeast, soy, animal or dairy products,
fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified
organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
BCM-95® is an exclusivity licensed registered trademark to Arjuna Natural Pvt Lt
Protected under US patents 7,883,728; 7,736,679; and 7,879,373.
DIRECTIONS FOR USE
Take one capsule twice daily, or as directed by your health
care practitioner.
Consult your health care practitioner prior to use. Individuals
taking medication, especially blood thinners or for cancer,
should discuss potential interactions with their health care
practitioner. Do not use if tamper seal is damaged.
SAFETY & DOSING
Turmeric has been safely consumed for thousands of years,
and its medicinal compound curcumin has an outstanding
safety profile. Phase I clinical trials using up to 8 g/d for
four months did not result in discernable toxicities. Mild
gastrointestinal distress can sometimes accompany curcumin
supplementation, but this may be minimized by consuming
the supplement with food. Current doses in clinical trials
using BCM-95 range from 500 mg/d to 1000 mg/d.
STORAGE
Keep closed in a cool, dry place out of reach of children.
PRODUCT BENEFITS*
• Provides antioxidant and cell-protective activity
• Supports joint health and helps relieve minor pain
associated with physical activity
• Supports the health of organs and systems by
modulating the production of cytokines and other
signaling molecules
• Supports the body’s efforts to promote healthy cell
growth and inhibit unhealthy cell growth in certain
cell lines
• Supports brain/neuronal health and a healthy mood
• Supports a healthy microbial environment
Curcumin+ features BCM-95®—a 100% pure turmeric
extract standardized to curcumin, demethoxycurcumin,
bisdemethoxycurcumin, and essential oils of turmeric
rhizome. This natural composition optimizes bioavailability
and reflects true turmeric identity to deliver optimal health
benefits. BCM-95 has been extensively studied and shows
broad efficacy without the use of phospholipids, excipients,
additives, carriers, nanotechnology, or bioenhancers.
Curcumin, the principal curcuminoid in turmeric, has been
the subject of vast research in recent years. The pleiotropic
nature of curcumin’s biological effects make it an interesting
compound to researchers who study common chronic
health concerns, such as those associated with joints, the
cardiovascular system, glucose metabolism, brain function,
mood, and cell-cycle regulation.[1-6]
The mechanisms underlying curcumin’s effects are diverse
and have not been fully elucidated, but it is known that
curcumin has powerful antioxidant activity and that it has
multiple molecular targets, including transcription factors, cell
cycle proteins, cytokines, chemokines, enzymes (e.g., COX-2),
receptors, and adhesion molecules.[7] These effects make
curcumin applicable to a wide array of clinical presentations.
KEY INGREDIENTS
Patented Formulation: BCM-95® — While the beneficial
effects of curcumin are hardly arguable, an area of
intense research is how to make curcumin more
bioavailable. Poor absorption in the gastrointestinal (GI)
tract, rapid metabolism, and rapid systemic elimination
are characteristics of commercially available curcumin
preparations. While investigating a way to overcome
these challenges, scientists discovered they could take
advantage of the synergism between the curcuminoids
and the sesquiterpenoids (essential oils) naturally present
in turmeric.[7] This discovery resulted in the development of
BCM-95—a 100% natural whole turmeric extract composed
of 86% curcuminoids (curcumin, demethoxycurcuminoid,
and bisdemethoxycurcuminoid) and 7%-9% essential oils.
Essential oils are a natural component of the turmeric
rhizome. Not only do they enhance absorption of
curcuminoids, but they also impart health benefits.[8-10]
The essential oils found in BCM-95 are extracted using
double steam distillation. Essential oils comprise 7% to
9% of turmeric, with 50% of that being ar-turmerone,
alpha-turmerone, and beta-turmerone. Some of the other
essential oils present in BCM-95 include ar-curcumene,
alpha-curcumene, zingiberene, beta- sesquiphella,
beta-atlantone, and germacrone.
BCM-95 STUDIES
To date, BCM-95 is backed by more than 21 published
studies and over 12 years of research conducted around
the world. Unlike many commercially available curcumin
formulas, the bioavailability, safety, and efficacy of BCM-95
curcumin has been demonstrated in numerous preclinical
and human studies. The following areas illustrate the massive
body of research behind BCM-95 in relation to common
health concerns: colon health[13-17], mood and stress[5,18-20],
cognitive health[6], joint health[2,21], urinary health[22], cytokine
modulation[23,24], prostate health[25-27], breast health[28], and
cardiovascular health.[29]
As an example of the findings, in an eight-week randomized,
double-blind, placebo-controlled trial (n=56), ingestion of 500
mg BCM-95 twice daily resulted in significant improvements in
mood-related parameters during weeks four to eight.[20] These
findings are supported by related research into curcumin’s
effect on mood.[18,19] In another study, the effects of BCM-95
on joints were evaluated. The BCM-95 group (500 mg for
eight weeks) showed the highest percent of improvement in
scoring related to joint health and comfort.[2]
In addition to the aforementioned published studies, eight
human clinical trials using BCM-95 for periods of 21 days to
one year are currently underway at prestigious institutions,
including several at Baylor University Medical Center at Dallas.
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