N-Acetyl-L-Cysteine is a source of L-cysteine, the amino acid and precursor required for glutathione formation. NAC and glutathione support antioxidant and detoxification activity throughout the body.
- Serving size: 2 Capsules Amount % Daily
Servings per container: 60 Per Serving Value
N-Acetyl-L-Cysteine 1.2 g **
** Daily Value Not Established
Other Ingredients: HPMC (capsule), stearic acid, magnesium stearate, and silica.
Does Not Contain: Wheat, gluten, corn, yeast, soy, animal or dairy products, fish,
shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified
organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
NAC (N-acetyl-cysteine), a sulfur-containing derivative
of the amino acid L-cysteine, supports antioxidant and
detoxification mechanisms in the body. NAC supports
antioxidant activity by neutralizing hydrogen peroxide,
hypochlorous acid, and the highly reactive hydroxyl radical
and also serves as a source of sulfhydryl groups. In addition,
NAC enhances production of the tripeptide glutathione—a
key component of both antioxidant and detoxification
enzymes.*[1]
NAC is recognized for its support of normal mucous
production and may positively support respiratory function
and eye health, especially when consumed over a prolonged
period.[1-3] Research suggests that NAC may protect cell
and tissue health by supporting normal metal status in the
body.*[1,4,5]
Glutathione. While the absorption of oral glutathione may
be limited,[6] supplementation with NAC may significantly
increase circulating levels of glutathione in the body.[7,8]
Once NAC promotes production of glutathione, glutathione
is incorporated into crucial antioxidant enzymes (e.g.,
glutathione peroxidase and glutathione reductase) and
detoxification enzymes (glutathione S-transferases). Through
the activity of these enzymes, glutathione directly supports
antioxidant activity, phase II detoxification, and the normal
breakdown of metabolites, toxins, and other compounds in
the body. Glutathione also participates in fatty acid synthesis
and amino acid transport across the cell membrane.*[1]
A variety of factors may determine glutathione requirements,
including level of exposure to toxins, increased phase
I detoxification activity, and overall need for antioxidant
support. Maintaining glutathione levels may be important
to maintaining the health of the respiratory, hepatic,
and immune systems, as well as supporting antioxidant
protection of lipids and proteins and supporting the normal
response to inflammation.[7-13] Levels of endogenous
antioxidants, including glutathione, may decrease with age.[14]
It is important to maintain adequate levels of glutathione in
the body to support overall health and well-being throughout
the lifespan.*
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