Consult your healthcare provider before taking this product if you are taking prescription medications (e.g. MAOI and SSRI antidepressants) for depression. Concomitant use of L-tryptophan with antidepressant medications has the potential to increase the risk of serotonin syndrome, characterized by symptoms like confusion, sweating, agitation, nausea, involuntary muscle contractions, and racing heartbeat. Do not use L-tryptophan before driving or operating heavy machinery.